As a cannabis grower, manufacturer, or processor, you want to stay on top of market developments. That includes considering the hundreds of other therapeutic components present in hemp & cannabis in addition to THC and CBD. Lesser-known cannabinoids will soon gain household names as buyers learn more about the plant’s therapeutic properties. Why not look into cannabidiolic acid (CBDa), which has the potential to rival CBD in terms of therapeutic effectiveness and potency?

We’ll go over the advantages, science, and business potential so you can make an educated decision about selling expensive CBDa hemp or cannabis goods.


Cannabis and hemp plants create over 100 chemical compounds, including CBDa. It is well known that the acidic predecessor to cannabidiol (CBD), is converted to CBD when heated and exposed to light. Scientists didn’t realize CBDa could survive digestion until recently, and they didn’t think it had any medical use. However, it turns out that CBDa has its own set of therapeutic properties.



CBDa could potentially stop breast cancer cell migration, according to a 2012 study published in Toxicology Letters Journal. This was one of the first experiments to look at whether CBDa was biologically active on its own. CBDa suppressed the inflammatory enzyme of breast cancer that is also important for cancer cell metastasis (spreading), according to a second study published in the Journal of Toxicological Sciences in 2014. COX-2 is an enzyme detected in approximately half of all cases of breast cancer.


CBDa has anti-inflammatory benefits across a wide range of conditions, including injuries, pain, breast cancer, and inflammatory diseases, because of its capacity to target COX-2. CBDa may potentially be a natural alternative to NSAIDs, which are nonsteroidal anti-inflammatory medicines that function by targeting COX-2. While NSAIDs are used to treat common ailments such as arthritis, menstruation, osteoarthritis, or even sports injuries, some people experience an increased risk of strokes and heart attacks. More research is needed on all of the illnesses indicated above, but current evidence suggests CBDA For Sale could provide relief–without the risk of hazardous side effects.


Nausea and vomiting are common side effects of chemotherapy, and most treatments only provide temporary relief. Many procedures just prevent vomiting while leaving patients with a distressing, persistent sense of nausea. CBDa, like CBD, appears to have anti-nausea qualities, according to a study. CBDa may be more beneficial than CBD, according to some research, because it is more easily broken down by the body.

CBDa was found to be substantially more effective than CBD at inhibiting nausea by activating the 5-HT (1A) serotonin receptor in an animal study published in the British Journal of Pharmacology. However, more research, particularly in humans, is required to corroborate this result.


CBDa may be a useful anti-convulsive and anti-seizure medication because it activates 5-HT serotonin receptors. A review of medical cannabis evidence was published in the journal Frontiers of Integrative Neuroscience in 2018. The scientists stated in their paper that CBDa has a 100-fold higher affinity on 5-HT (1A) receptors than CBD.

CBD is a well-recognized and well-proven anti-seizure medication. It was even used to make the first cannabis-derived prescription medicine to be approved by the us Food and Drug Administration (Epidiolex) (US FDA). The drug’s producer, GW Pharmaceuticals, had to examine the effects of CBDa as part of the approval procedure. The study indicated that high concentration CBDa alone is a successful treatment for epilepsy as a result of this process.


Though research is still in its early stages, some evidence suggests that CBDa may help with depression by having a similar affinity for the 5-HT (1A) serotonin receptor. Oral CBDa could be a strong treatment for treating depression, according to a recent animal study from Israel. While the more human clinical study is needed, some scientists believe CBDa could cure mental illness in the same manner as prescription serotonin uptake inhibitors (SSRIs) do now.